Psychotropic Drug Indications- MPR

Psychotropic Drug Indications

PSYCHOTROPIC DRUG INDICATIONS
Generic	Brand	Form	Bipolar Disorder				MDD	TRD	PMDD	Schizophrenia	Others⁴
Generic	Brand	Form	Mania	Depression	Mixed Episodes	Maintenance	MDD	TRD	PMDD	Schizophrenia	Others⁴
ATYPICAL ANTIPSYCHOTICS
aripiprazole	—	tabs, ODT, oral soln	✓		✓	✓	✓¹			✓	✓
	Abilify	tabs	✓		✓	✓	✓¹			✓	✓
	Abilify Asimtufii	ext-rel IM inj				✓				✓
	Abilify Maintena	ext-rel IM inj				✓				✓
	Abilify Mycite	tabs with sensor	✓		✓	✓	✓¹			✓
aripiprazole lauroxil	Aristada	ext-rel IM inj								✓
aripiprazole lauroxil	Aristada Initio	ext-rel IM inj								✓
asenapine	Saphris	sublingual tabs	✓		✓	✓				✓
asenapine	Secuado	transdermal system								✓
brexpiprazole	Rexulti	tabs					✓¹			✓	✓
cariprazine	Vraylar	caps	✓	✓	✓		✓¹			✓
clozapine	Clozaril	tabs								✓	✓
clozapine	Versacloz	oral susp								✓	✓
iloperidone	Fanapt	tabs								✓
lumateperone	Caplyta	caps		✓						✓
lurasidone	Latuda	tabs		✓						✓
olanzapine	Zyprexa	tabs	✓	✓²	✓	✓		✓²		✓
	Zyprexa	IM inj									✓
	Zyprexa Relprevv	ext‑rel IM inj								✓
	Zyprexa Zydis	ODT	✓	✓²	✓	✓		✓²		✓
paliperidone	Invega	ext-rel tabs								✓	✓
	Invega Hafyera	ext-rel IM inj								✓
	Invega Sustenna	ext-rel IM inj								✓	✓
	Invega Trinza	ext-rel IM inj								✓
pimavanserin	Nuplazid	tabs, caps									✓
quetiapine	Seroquel	tabs	✓	✓		✓¹				✓
quetiapine	Seroquel XR	ext‑rel tabs	✓	✓	✓	✓¹	✓¹			✓
risperidone	—	ODT	✓		✓					✓	✓
	Perseris	ext-rel SC inj								✓
	Risperdal	tabs, oral soln	✓		✓					✓	✓
	Risperdal Consta	ext-rel IM inj				✓				✓
	Uzedy	ext-rel SC inj								✓
ziprasidone	Geodon	caps	✓		✓	✓¹				✓
ziprasidone	Geodon	IM inj									✓
MONOAMINE OXIDASE INHIBITORS (MAOIs)
phenelzine	Nardil	tabs					✓
selegiline	EMSAM	trans– dermal system					✓
tranylcy– promine	Parnate	tabs					✓
SEROTONIN AND NOREPINEPHRINE REUPTAKE INHIBITORS (SNRIs)
desvenla– faxine	—	ext‑rel tabs					✓
desvenla– faxine	Pristiq	ext‑rel tabs					✓
duloxetine	Cymbalta	caps					✓				✓
levomil– nacipran	Fetzima	ext‑rel caps					✓
venlafaxine	—	scored tabs					✓
venlafaxine	Effexor XR	ext‑rel caps					✓				✓
SELECTIVE SEROTONIN REUPTAKE INHIBITORS (SSRIs)
citalopram	Celexa	scored tabs					✓
escitalopram	—	oral soln					✓				✓
escitalopram	Lexapro	scored tabs					✓				✓
fluoxetine	—	tabs, oral soln		✓³			✓	✓³	✓⁷		✓
fluoxetine	Prozac	caps		✓³			✓	✓³			✓
paroxetine	Paxil	scored tabs, oral susp					✓				✓
paroxetine	Paxil CR	controlled-rel tabs					✓		✓		✓
sertraline	Zoloft	scored tabs, oral conc					✓		✓		✓

Generic	Brand	Form	Bipolar Disorder				MDD	TRD	PMDD	Schizophrenia	Others⁴
Generic	Brand	Form	Mania	Depression	Mixed Episodes	Maintenance	MDD	TRD	PMDD	Schizophrenia	Others⁴
SSRI AND 5-HT_1A RECEPTOR PARTIAL AGONIST
vilazodone	Viibryd	tabs					✓
SEROTONERGIC ANTIDEPRESSANT
vortioxetine	Trintellix	tabs					✓
TETRACYCLIC ANTIDEPRESSANTS
mirtazapine	Remeron	scored tabs					✓
mirtazapine	Remeron Soltab	ODT					✓
TRICYCLIC ANTIDEPRESSANTS (TCAs)
amitriptyline	—	tabs					✓
amoxapine	—	tabs					✓				✓
desipramine	Norpramin	tabs					✓
doxepin	—	caps, oral conc					✓				✓
imipramine	Tofranil	tabs					✓
nortriptyline	Pamelor	caps					✓
protriptyline	—	tabs					✓
trimipramine	—	caps					✓
FIXED-DOSE COMBINATION
dextromethorphan + bupropion	Auvelity	ext-rel tabs					✓
olanzapine + fluoxetine	Symbyax	caps		✓				✓
olanzapine + samidorphan	Lybalvi	tabs	✓		✓	✓				✓
OTHER CLASSES
brexanolone	Zulresso	IV infusion									✓
bupropion HBr	Aplenzin	ext‑rel tabs					✓				✓
bupropion HCl	—	tabs					✓
	Forfivo XL	ext-rel tabs					✓
	Wellbutrin SR	sust-rel tabs					✓
	Wellbutrin XL	ext‑rel tabs					✓				✓
carbamaz– epine	Equetro	ext‑rel caps	✓		✓
dexmedeto– midine	Igalmi	SL film									✓
divalproex sodium	Depakote	del‑rel tabs	✓
divalproex sodium	Depakote ER	ext‑rel tabs	✓		✓
esketamine	Spravato	nasal spray					✓^5,6	✓⁵
haloperidol	—	tabs, IM inj								✓	✓
haloperidol	Haldol Decanoate	sust-rel IM inj								✓
lamotrigine	Lamictal	scored tabs, chewable dispersible tabs				✓
lamotrigine	Lamictal	ODT				✓
lithium carbonate	—	caps, tabs	✓		✓	✓
lithium carbonate	Lithobid	ext-rel tabs	✓			✓
lithium ion	—	oral soln	✓		✓	✓
nefazodone	—	scored tabs					✓
trazodone	—	scored tabs					✓
trazodone	NOTES
Key: conc = concentrate; del‑rel = delayed release; ext‑rel = extended-release; MDD = major depressive disorder; ODT = orally-disintegrating tabs; PMDD = premenstrual dysphoric disorder; SL = sublingual; susp = suspension; sust-rel = sustained-release; TRD = treatment resistant depression. ¹For adjunctive treatment. ²Use in combination with fluoxetine. ³Use in combination with olanzapine. ⁴Others include agitation due to bipolar/schizophrenia, anxiety, panic disorder, seasonal affective disorder, tourette’s, postpartum depression, schizoaffective disorder, Parkinson’s disease psychosis, agitation associated with dementia due to Alzheimer disease, others; see drug monograph or full labeling. ⁵Use in conjunction with an oral antidepressant. Not an inclusive list of medications and/or official indications. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling. ⁶MDD with acute suicidal ideation or behavior ⁷Fluoxetine 10mg and 20mg tabs have indication for PMDD (formerly brand Sarafem). (Rev. 8/2023)

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