Topical Acne Treatments- MPR

Topical Acne Treatments

TOPICAL ACNE TREATMENTS
Generic	Brand		Strength	Form	Dose
ANDROGEN RECEPTOR INHIBITOR
clascoterone	Winlevi	Rx	1%	crm	Adults: Apply thin layer to clean, dry affected area twice daily (AM and PM). Children: <12yrs: Not established.
ANTIBACTERIAL/ANTIKERATINIZING
azelaic acid	Azelex	Rx	20%	crm	Adults: Gently massage thin film to affected areas twice daily (AM and PM) to clean, dry skin. Wash hands after use. May decrease to once daily if persistent irritation occurs. Children: Not recommended.
ANTIBACTERIAL/KERATOLYTIC
benzoyl peroxide	—	Rx	5%, 10%	water-base gel	Adults: Apply to cleansed area 1−2 times daily Children: Not recommended.
benzoyl peroxide	—	Rx	5%, 10%	wash	Adults: Wash affected area 1−2 times daily; rinse Children: Not recommended.
ANTIMICROBIALS
clinda– mycin	Cleocin T	Rx	1%	lotion, gel	Adults: Apply thin film twice daily Children: Not established.
	Clindagel	Rx	1%	gel	Adults: Apply thin film once daily Children: Not recommended.
	Clindets	Rx	1%	pledgets⁵	Adults: Apply thin film twice daily Children: Not recommended.
	Evoclin	Rx	1%	foam³	Adults: Apply once daily to clean, dry skin Children: <12yrs: Not established.
erythro– mycin	—	Rx	2%	gel	Adults: Apply thin film 1−2 times daily Children: Not established.
	—	Rx	2%	soln, pads³	Adults: Apply with applicator or pads to clean, dry skin twice daily Children: Not recommended.
	Ery 2% Pads	Rx	2%	pledgets³	Adults: Rub over cleansed area twice daily (AM & PM) Children: Not applicable.
minocycline	Amzeeq	Rx	4%	foam³	Adults and Children: <9yrs: Not established. ≥9yrs: Apply at the same time each day ≥1hr before bedtime. Rub gently into affected area(s); repeat as needed. Avoid bathing, showering or swimming for ≥1hr after application.
sodium sulfacet– amide	Klaron	Rx	10%	lotion	Adults: Apply thin film twice daily to affected areas Children: Not recommended.
KERATOLYTIC
salicylic acid	Phisoderm Anti-Blemish Body Wash	OTC	2%	body wash	Adults: Massage onto skin; rinse Children: Not applicable.
salicylic acid	Phisoderm Anti-Blemish Gel Facial Wash	OTC	2%	gel	Adults: Massage onto skin twice daily; rinse Children: Not applicable.
RETINOIDS
adapalene	Differin	Rx	0.1%	crm⁶	Adults: Apply thin film to affected areas once daily after washing. Reduce frequency or discontinue if prolonged or severe irritation occurs. Children: Not established.
		OTC	0.1%	gel⁶
		Rx	0.3%	gel⁶
		Rx	0.1%	lotion
tazarotene	Arazlo	Rx	0.045%	lotion	Adults and Children: <9yrs: Not established. ≥9yrs: Apply a thin film to affected areas once daily. Women of childbearing potential: begin therapy during normal menses.
	Fabior	Rx	0.1%	foam	Adults: Apply thin layer to clean, dry affected area (face, upper trunk) once daily in PM. Women of childbearing potential: Begin therapy during normal menses. Children: Not recommended.
	Tazorac	Rx	0.05%*, 0.1%	crm, gel	Adults: Apply thin film of 0.1% strength to lesions on clean, dry face once daily in the PM. Women of childbearing potential: Begin therapy during normal menses. Children: <12yrs: Not established.
tretinoin	Altreno	Rx	0.05%	lotion⁴	Adults and Children: <9yrs: Not established. ≥9yrs: Apply thin layer to affected areas once daily. Reduce frequency or discontinue if severe irritation occurs.
	Atralin	Rx	0.05%	gel^2,4	Adults and Children: <10yrs: Not recommended. ≥10yrs: Apply sparingly at bedtime to clean skin once daily. Adjust amount and frequency as tolerated.
	Avita	Rx	0.025%	crm, gel	Adults: Apply sparingly to clean, dry skin once daily at bedtime. If irritation develops, adjust dose or frequency as tolerated and needed. Children: Not recommended.
	Retin‑A	Rx	0.025%, 0.05%, 0.1%	crm
	Retin‑A	Rx	0.01%, 0.025%	gel¹
	Retin‑A Micro	Rx	0.04%, 0.08%, 0.1%	aqueous gel
trifarotene	Aklief	Rx	0.005%	crm	Adults and Children: <9yrs: Not established. ≥9yrs: Apply a thin layer to affected areas once daily in the PM. Face: 1 pump actuation. Upper trunk: 2 pump actuations; may use 1 additional pump actuation for middle and lower back, if needed.
SULFONE
dapsone	Aczone	Rx	5%	gel	Adults: Apply pea-sized amount to affected area twice daily (AM & PM). Wash hands after use. Reevaluate if no improvement after 12wks. Children: <12yrs: Not recommended.
dapsone	Aczone	Rx	7.5%	gel	Adults and Children: <9yrs: Not established. ≥9yrs: Apply pea-sized amount to affected area once daily. Wash hands after use. Reevaluate if no improvement after 12wks.
COMBINATION AGENTS
adapalene/ benzoyl peroxide	Epiduo Forte Gel	Rx	0.3%/ 2.5%	gel	Adults: Apply thin film to affected areas of face and/or trunk once daily after washing. Use a pea-sized amount for each area of the face. Reduce frequency or discontinue if prolonged or severe irritation occurs. Children: <12yrs: Not established.
adapalene/ benzoyl peroxide	Epiduo Gel	Rx	0.1%/ 2.5%	gel	Adults and Children: <9yrs: Not established. ≥9yrs: Apply thin film to clean affected areas (face, trunk) once daily. Use a pea-sized amount for each area of the face. Reduce frequency or discontinue if prolonged or severe irritation occurs.
clinda– mycin/ benzoyl peroxide	Acanya	Rx	1.2%/ 2.5%	gel	Adults: Apply pea-sized amount in a thin layer to clean, dry face once daily. Wash hands after use. Children: Not recommended.
	Benzaclin	Rx	1%/5%	gel	Adults: Apply twice daily Children: Not recommended.
	Duac	Rx	1%/5%	gel	Adults: Apply to clean, dry skin once daily in the evening Children: Not recommended.
	Onexton	Rx	1.2%/ 3.75%	gel	Adults: Apply a pea-sized amount once daily Children: Not established.
erythro– mycin/ benzoyl peroxide	Benzamycin	Rx	3%/5%	gel	Adults: Apply to clean, dry skin twice daily Children: Not recommended.
tretinoin/ benzoyl peroxide	Twyneo	Rx	0.1%/ 3%	crm	Adults and Children: <9yrs: Not established. ≥9yrs: Apply thin layer to clean, dry skin once daily.
clindamycin/ tretinoin	Ziana	Rx	1.2%/ 0.025%	gel	Adults: Apply thin film to clean, dry face once daily at bedtime Children: Not recommended.
NOTES
*Only 0.1% indicated for mild to moderate acne vulgaris ¹contains cetearyl alcohol ²contains parabens ³contains alcohol ⁴contains benzyl alcohol ⁵contains isopropyl alcohol ⁶alcohol‑free Not an inclusive list of medications and/or doses. Please see drug monograph at www.eMPR.com, contact company for full drug labeling and/or consult your healthcare provider. Contains FDA‑approved doses only for Rx products. (Rev. 1/2023)

Want to read more?