Concerta Generic Name & Formulations
Legal Class
General Description
Pharmacological Class
How Supplied
Manufacturer
Generic Availability
Mechanism of Action
Concerta Indications
Indications
Concerta Dosage and Administration
Adults and Children
Concerta Contraindications
Contraindications
During or within 14 days of MAOIs.
Concerta Boxed Warnings
Boxed Warning
Abuse, misuse, and addiction.
Concerta Warnings/Precautions
Warnings/Precautions
High potential for abuse, misuse, and addiction; assess patient's risk before prescribing. Assess for presence of cardiac disease before initiating. Avoid in known structural cardiac abnormalities, cardiomyopathy, serious arrhythmias, coronary artery disease, or other cardiac disease. Pre-existing psychotic disorder. Bipolar disorder. Screen for risk factors of developing a manic episode prior to initiation. Consider discontinuing if new psychotic/manic symptoms occur. Seizure disorder. Peripheral vasculopathy, including Raynaud's Phenomenon; monitor for digital changes. Preexisting GI narrowing. Risk for acute angle closure glaucoma. History of increased IOP or open angle glaucoma; monitor closely. Assess family history and evaluate for tics or Tourette’s syndrome before initiating; monitor for emergence or worsening, and discontinue if clinically appropriate. Monitor BP, HR, growth in children. Periodically monitor CBCs, differential, platelet counts during prolonged therapy. Reduce dose or discontinue if paradoxical aggravation of symptoms occurs. Reevaluate periodically. Pregnancy (Cat.C). Nursing mothers.
Concerta Pharmacokinetics
Absorption
Mean times to reach peak plasma concentration: 6–10 hours.
Elimination
Renal (90%). Half-life: ~3.5 hours.
Concerta Interactions
Interactions
See Contraindications. Hypertensive crisis with MAOIs. Caution with pressor agents. May potentiate coumarin anticoagulants, anticonvulsants (eg, phenobarbital, phenytoin, primidone), tricyclics, SSRIs. Risk of serotonin syndrome with serotonergic drugs. Concomitant halogenated anesthetics may increase the risk of sudden BP and HR increase during surgery; avoid use. Concomitant risperidone may increase risk of extrapyramidal symptoms; monitor.
Concerta Adverse Reactions
Adverse Reactions
Upper abdominal pain, decreased appetite, headache, dry mouth, nausea, insomnia, anxiety, dizziness, weight loss, irritability, hyperhidrosis; priapism, hypertension, tachycardia, visual disturbances, possible GI obstruction, motor/verbal tics.
Concerta Clinical Trials
See Literature
Concerta Note
Not Applicable
Concerta Patient Counseling
See Literature
Images
