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Miostat Generic Name & Formulations
Legal Class
Rx
General Description
Carbachol 0.01%; per mL; soln for intraocular inj.
Pharmacological Class
Cholinergic.
How Supplied
Single-use vial (1.5mL)—12
Manufacturer
Miostat Indications
Indications
To obtain miosis during eye surgery. To reduce the intensity of intraocular pressure elevation in the first 24 hours after cataract surgery.
Miostat Dosage and Administration
Adult
See full labeling. Withdraw contents into a dry sterile syringe and replace the needle with an atraumatic cannula prior to intraocular instillation. Gently instill no more than ½ mL into the anterior chamber; may be instilled before or after securing sutures. Usually within 2–5 mins after application for maximal miosis effects.
Children
Not established.
Miostat Contraindications
Not Applicable
Miostat Boxed Warnings
Not Applicable
Miostat Warnings/Precautions
Warnings/Precautions
For single-dose intraocular use only. Acute cardiac failure. Bronchial asthma. Peptic ulcer. Hyperthyroidism. GI spasm. Urinary tract obstruction. Parkinson's disease. Latex allergy. Pregnancy (Cat.C). Nursing mothers.
Miostat Pharmacokinetics
See Literature
Miostat Interactions
Not Applicable
Miostat Adverse Reactions
Adverse Reactions
Corneal clouding, persistent bullous keratopathy, retinal detachment, postoperative iritis; flushing, sweating, epigastric distress, abdominal cramps, tightness in urinary bladder, headache.
Miostat Clinical Trials
See Literature
Miostat Note
Not Applicable
Miostat Patient Counseling
See Literature
