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Ibsrela Generic Name & Formulations
Legal Class
Rx
General Description
Tenapanor (as HCl) 50mg; tabs.
Pharmacological Class
Sodium/hydrogen exchanger 3 (NHE3) inhibitor.
How Supplied
Tabs—60
Manufacturer
Generic Availability
NO
Ibsrela Indications
Indications
Irritable bowel syndrome with constipation (IBS-C).
Ibsrela Dosage and Administration
Adult
Take immediately prior to breakfast (or the first meal of the day) and prior to dinner. 50mg twice daily.
Children
<18yrs: not established.
Ibsrela Contraindications
Contraindications
Patients <6yrs of age. Known or suspected mechanical GI obstruction.
Ibsrela Boxed Warnings
Not Applicable
Ibsrela Warnings/Precautions
Warnings/Precautions
Avoid use in patients 6–<12yrs of age. Suspend dosing and rehydrate if severe diarrhea occurs. Pregnancy. Nursing mothers.
Ibsrela Pharmacokinetics
See Literature
Ibsrela Interactions
Interactions
Antagonizes OATP2B1 substrates (eg, enalapril); monitor and increase dosage of substrates as needed.
Ibsrela Adverse Reactions
Adverse Reactions
Diarrhea, abdominal distension, flatulence, dizziness.
Ibsrela Clinical Trials
See Literature
Ibsrela Note
Not Applicable
Ibsrela Patient Counseling
See Literature
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