Bentyl Injection

— THERAPEUTIC CATEGORIES —
  • Hyperacidity, GERD, and ulcers

Bentyl Injection Generic Name & Formulations

General Description

Dicyclomine HCl 10mg/mL; soln for IM inj.

Pharmacological Class

Anticholinergic.

How Supplied

Caps, tabs, syrup—contact supplier; Amps (2mL)—5

Manufacturer

Bentyl Injection Indications

Indications

Irritable bowel syndrome.

Bentyl Injection Dosage and Administration

Adult

Give by IM route only. 10–20mg four times daily for max 1–2 days when oral therapy is not feasible.

Children

<6mos: see Contraindications. ≥6mos: consult manufacturer.

Bentyl Injection Contraindications

Contraindications

Glaucoma. Unstable cardiovascular status. GI or urinary tract obstruction. Severe ulcerative colitis. Myasthenia gravis. Reflux esophagitis. Children <6months of age. Nursing mothers.

Bentyl Injection Boxed Warnings

Not Applicable

Bentyl Injection Warnings/Precautions

Warnings/Precautions

Inj: avoid IV administration (may cause thrombosis, inj site reactions). Autonomic neuropathy. Hepatic or renal impairment. Cardiovascular disease. Hypertension. Hyperthyroidism. Salmonella dysentery. Toxic megacolon. Ulcerative colitis. GI or GU obstruction. High environmental temperature. Diarrhea. Elderly. Debilitated. Pregnancy (Cat.B).

Bentyl Injection Pharmacokinetics

See Literature

Bentyl Injection Interactions

Interactions

Antacids may inhibit absorption; avoid. May antagonize anti-glaucoma agents or drugs that alter GI motility (eg, metoclopramide). Antagonized by agents used to treat achlorhydria and those used to test gastric secretion. Additive anticholinergic effects with other anticholinergics, narcotic analgesics, type I antiarrhythmics, antihistamines, antipsychotics, tricyclics, amantadine, benzodiazepines, MAOIs, nitrites, nitrates, sympathomimetics. May affect absorption of sust rel dosage forms.

Bentyl Injection Adverse Reactions

Adverse Reactions

Dizziness, dry mouth, blurred vision, nausea, somnolence, asthenia, and nervousness; cardiovascular and CNS symptoms (eg, psychosis, delirium). Fatal reactions have occurred in infants.

Bentyl Injection Clinical Trials

See Literature

Bentyl Injection Note

Notes

Formerly known under the brand name Bentyl.

Bentyl Injection Patient Counseling

See Literature