Clobex Generic Name & Formulations
Legal Class
Rx
General Description
Clobetasol propionate 0.05%; lotion.
See Also
How Supplied
Lotion—2oz, 4oz; Shampoo—4oz; Spray—2oz, 4.25oz
Manufacturer
Clobex Indications
Indications
Corticosteroid-responsive dermatoses.
Clobex Dosage and Administration
Adult
Apply thin layer twice daily (AM & PM); max 50 g/week and 2 consecutive weeks' treatment per course. Moderate-to-severe plaque-type psoriasis: may use on up to 10% BSA for up to 4 consecutive weeks.
Children
≤18yrs: not recommended.
Clobex Contraindications
Contraindications
Do not use superpotent forms on face, groin, or axillae. Exclude viral disease (eg, chickenpox, measles).
Clobex Boxed Warnings
Not Applicable
Clobex Warnings/Precautions
Warnings/Precautions
Treat infection if present; discontinue if infection persists or worsens. Avoid contact with eyes, or on diaper dermatitis or pre-existing skin atrophy. Do not use fluorinated steroids longer than 1 week on the face. Avoid abrupt cessation in chronic use. Systemic absorption increased by broken or inflamed skin, prolonged use, application to large surface area, or use of occlusive dressings. Occlude only if necessary; do not occlude higher potency products. Monitor adrenal function in children if a high potency product or occlusion is used, and in adults if more than 50g weekly of a high potency product is used. Increased risks of glaucoma, posterior subcapsular cataract. Discontinue or reduce dose or potency if HPA axis suppression, Cushing's syndrome, hyperglycemia, glucosuria, or irritation occurs. Use lowest effective dose and potency (esp. in children). Use caution if applying to face or body folds. Do not use continuously or for prophylaxis. Foams are flammable. Reevaluate periodically. Pregnancy. Nursing mothers.
Clobex Pharmacokinetics
See Literature
Clobex Interactions
Not Applicable
Clobex Adverse Reactions
Adverse Reactions
Burning, stinging, pruritus, erythema, skin atrophy, striae, miliaria, secondary infections, hypopigmentation, folliculitis, hypertrichosis, acneiform eruptions, dermal cracking and fissuring, telangiectasia, contact dermatitis, other local effects, immunosuppression, masks infections, visual symptoms, HPA axis suppression (esp. in children).
Clobex Clinical Trials
See Literature
Clobex Note
Not Applicable
Clobex Patient Counseling
See Literature