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Catapres-tts Generic Name & Formulations
Legal Class
Rx
General Description
Clonidine 0.1mg/day, 0.2mg/day, 0.3mg/day; each transdermal patch delivers dose for 1 week.
Pharmacological Class
Central alpha agonist.
See Also
How Supplied
Tabs—100; Patch—4
Manufacturer
Catapres-tts Indications
Indications
Hypertension.
Catapres-tts Dosage and Administration
Adult
Apply to intact, hairless area of upper arm or anterior torso; rotate application sites. Taper withdrawal of other antihypertensives. Initially one 0.1mg/day patch weekly; may increase after 1–2 weeks; max 0.6mg/day.
Children
Not established.
Catapres-tts Contraindications
Not Applicable
Catapres-tts Boxed Warnings
Not Applicable
Catapres-tts Warnings/Precautions
Warnings/Precautions
Sinus node dysfunction. AV block. Pheochromocytoma: not effective. Conduction disturbances. Renal dysfunction. Avoid abrupt cessation. If local reaction occurs from patch, using tabs may cause generalized rash. Discontinue 4hrs before surgery; resume as soon as possible after surgery. Patch: remove before defibrillation, cardioversion, or MRI. Pregnancy (Cat.C). Nursing mothers.
Catapres-tts Pharmacokinetics
See Literature
Catapres-tts Interactions
Interactions
Antagonized by tricyclic antidepressants. Potentiates CNS depressants. Orthostatic regulation disturbances (eg, orthostatic hypotension, dizziness, fatigue) possible with neuroleptics. Monitor heart rate in patients receiving agents known to affect sinus node function or AV nodal conduction (eg, digitalis, calcium channel blockers, β-blockers).
Catapres-tts Adverse Reactions
Adverse Reactions
Dry mouth, dry eye, drowsiness, dizziness, weakness, constipation, sedation, rash, myalgia, urticaria, nausea, insomnia, agitation, orthostatic hypotension, impotence, arrhythmias.
Catapres-tts Clinical Trials
See Literature
Catapres-tts Note
Not Applicable
Catapres-tts Patient Counseling
See Literature
